Our Science
At Anagram, we are using the power of orally delivered enzyme therapeutics to address significant unmet needs in malabsorption syndromes and nutrient metabolism disorders, focusing on diseases where we believe we have a high probability of technical success.
- Enzymes are ideal therapeutics — they bind to specific substrates (e.g., lipase for fats) to exert a precise therapeutic effect.
- As large molecules, orally delivered enzymes function within the gastrointestinal tract and are not systemically absorbed, providing a significant safety advantage.
Our experience and the novel technologies we use enable us to address one of the field's most persistent challenges: the gastric environment is too harsh for most orally delivered enzymes to survive and remain therapeutically effective. We are working to solve that.
We use decades of experience to understand gastrointestinal physiology for each disease we target and apply sensitive testing tools to precisely engineer novel, stable oral enzyme therapies. We partner with the best scientific minds and collaborators from around the world to deliver better treatment options.
anagram /ăn′ə-grăm″/ noun A word or phrase formed by reordering the letters of another word or phrase.
An anagram takes existing elements and, through deliberate rearrangement, creates something new. So do we.
